Article
Improved stress resistance and ethanol production by segmental haploidization of the diploid genome in Saccharomyces cerevisiae.
Journal of bioscience and bioengineering - 1 Jun 2016
Kaboli Saeed, Miyamoto Tetsuya, Sunada Keisuke, Sasano Yu, Sugiyama Minetaka, Harashima Satoshi
Abstract excerpt
Saccharomyces cerevisiae strains from industrial and natural geographical environments are reported to show great variation in copy number of chromosomal regions. Such variation contributes to the mechanisms underlying adaptation to different environments. Here, we created and phenotypically analyzed segmentally haploidized strains, each harboring a deletion of one copy of approximately 100-300 kb of the left or...
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