Article
Large scale deletions in the Saccharomyces cerevisiae genome create strains with altered regulation of carbon metabolism.
Applied microbiology and biotechnology - 1 Jun 2007
Murakami Kiriko, Tao Eriko, Ito Yuki, Sugiyama Minetaka, Kaneko Yoshinobu, Harashima Satoshi, Sumiya Takahiro, Nakamura Atsushi, Nishizawa Masafumi
Abstract excerpt
Saccharomyces cerevisiae, for centuries the yeast that has been the workhorse for the fermentative production of ethanol, is now also a model system for biological research. The recent development of chromosome-splitting techniques has enabled the manipulation of the yeast genome on a large scale, and this has allowed us to explore questions with both biological and industrial relevance, the number of genes...
Topics
- Carbon
- Chromosome Deletion
- Genome, Fungal
- Glucose
- Phenotype
- Saccharomyces cerevisiae