Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Refinement of the canine CD1 locus topology and investigation of antibody binding to recombinant canine CD1 isoforms.

Immunogenetics - 1 Mar 2016

Schjaerff Mette, Keller Stefan M, Fass Joseph, Froenicke Lutz, Grahn Robert A, Lyons Leslie, Affolter Verena K, Kristensen Annemarie T, Moore Peter F

Abstract excerpt

CD1 molecules are antigen-presenting glycoproteins primarily found on dendritic cells (DCs) responsible for lipid antigen presentation to CD1-restricted T cells. Despite their pivotal role in immunity, little is known about CD1 protein expression in dogs, notably due to lack of isoform-specific antibodies. The canine (Canis familiaris) CD1 locus was previously found to contain three functional CD1A genes:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antibody Specificity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antigens, CD1

Share to Genetic Loci

Share to Protein Isoforms

Share to Recombinant Fusion Proteins

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 26687789
DOI: 10.1007/s00251-015-0889-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Refinement of the canine CD1 locus topology and investigation of antibody binding to recombinant canine CD1 isoforms.PMID 26687789Read ↗

Crystal structure of the classical MHC-I molecule: insights into the MHC-I system in antiviral diseases in dogsSemantic proximity Read ↗

CD1: From Molecules to DiseasesSemantic proximity Read ↗

Unraveling IGK Locus in Dog Breeds: IMGT® New Insights into Canine ImmunogeneticsSemantic proximity Read ↗

Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family.Semantic proximity Read ↗

Chicken CD1 genes are located in the MHC: CD1 and endothelial protein C receptor genes constitute a distinct subfamily of class-I-like genes that predates the emergence of mammalsSemantic proximity Read ↗

Identification of allelic variants of the bovine immune regulatory molecule CEACAM1 implies a pathogen-driven evolution.Semantic proximity Read ↗

Synergism and complementarity between human CD1 AND MHC-restricted T cells, two lymphoid subsets directed against distinct antigenic worlds.Semantic proximity Read ↗

A new polymorphic epitope of bovine CD4 antigen evidenced by flow cytometry.Semantic proximity Read ↗

Characterization and allelic variation of the transporters associated with antigen processing (TAP) genes in the domestic dog (Canis lupus familiaris).Semantic proximity Read ↗

Identification of novel polymorphisms and two distinct haplotype structures in dog leukocyte antigen class I genes: DLA-88, DLA-12 and DLA-64.Semantic proximity Read ↗

Comprehensive annotation and evolutionary insights into the canine (Canis lupus familiaris) antigen receptor loci.Semantic proximity Read ↗

Structural characterization of two CD1A allelic variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.