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Article

Characterization and allelic variation of the transporters associated with antigen processing (TAP) genes in the domestic dog (Canis lupus familiaris).

Developmental and comparative immunology - 1 Dec 2013

Gojanovich Gregory S, Ross Peter, Holmer Savannah G, Holmes Jennifer C, Hess Paul R

Abstract excerpt

The function of the transporters associated with antigen processing (TAP) complex is to shuttle antigenic peptides from the cytosol to the endoplasmic reticulum to load MHC class I molecules for CD8(+) T-cell immunosurveillance. Here we report the promoter and coding regions of the canine TAP1 and TAP2 genes, which encode the homologous subunits forming the TAP heterodimer. By sampling genetically divergent...

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Share to Antigen Presentation
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class I

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 23892057
DOI: 10.1016/j.dci.2013.07.011
PMCID: PMC3846772

Genes

TAP2
TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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