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Article

Identification of allelic variants of the bovine immune regulatory molecule CEACAM1 implies a pathogen-driven evolution.

Gene - 15 Sept 2004

Kammerer Robert, Popp Tanja, Singer Bernhard B, Schlender Jörg, Zimmermann Wolfgang

Abstract excerpt

Carcinoembryonic antigen-related cell adhesion molecule (CEACAM1), the primordial member of the carcinoembryonic antigen (CEA) family, functions as a MHC-independent natural killer (NK) cell inhibitory receptor, regulates T and B cell proliferation, and induces dendritic cell (DC) maturation. Despite these fundamental functions, CEACAM1 and most of the CEA family members differ significantly in primates and...

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Source

Identifiers

PMID: 15363850
DOI: 10.1016/j.gene.2004.06.023

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Identification of allelic variants of the bovine immune regulatory molecule CEACAM1 implies a pathogen-driven evolution.PMID 15363850Read ↗

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On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human MalignanciesSemantic proximity Read ↗

Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selection.Semantic proximity Read ↗

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