Article
Structural characterization of two CD1A allelic variants.
Human immunology - 1 Oct 2001
Oteo M, Arribas P, Setién F, Parra J F, Mirones I, Gómez del Moral M, Martínez-Naves E
Abstract excerpt
CD1 molecules are specialized in presenting lipidic antigens to T lymphocytes. They are structurally and evolutionary related to MHC molecules and show very limited polymorphism. We have previously described and partially characterized a new human CD1A allele differing from the wild type CD1A by a substitution of Cysteine by Tryptophan at position 52 in the alpha1 domain of the CD1A molecule. The frequency of...
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