Article
Comprehensive annotation and evolutionary insights into the canine (Canis lupus familiaris) antigen receptor loci.
Immunogenetics - 1 Apr 2018
Martin Jolyon, Ponstingl Hannes, Lefranc Marie-Paule, Archer Joy, Sargan David, Bradley Allan
Abstract excerpt
Dogs are an excellent model for human disease. For example, the treatment of canine lymphoma has been predictive of the human response to that treatment. However, an incomplete picture of canine (Canis lupus familiaris) immunoglobulin (IG) and T cell receptor (TR)-or antigen receptor (AR)-gene loci has restricted their utility. This work advances the annotation of the canine AR loci and looks into breed-specific...
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