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Article

Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity.

Cellular microbiology - 1 Jun 2016

Kathum Omer Abid, Schräder Tobias, Anhlan Darisuren, Nordhoff Carolin, Liedmann Swantje, Pande Amit, Mellmann Alexander, Ehrhardt Christina, Wixler Viktor, Ludwig Stephan

Abstract excerpt

Phosphorylation and dephosphorylation acts as a fundamental molecular switch that alters protein function and thereby regulates many cellular processes. The non-structural protein 1 (NS1) of influenza A virus is an important factor regulating virulence by counteracting cellular immune responses against viral infection. NS1 was shown to be phosphorylated at several sites; however, so far, no function has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26687707
DOI: 10.1111/cmi.12559
PMCID: PMC5066752

Genes

TRIM25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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