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Article

Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Feb 2016

Friedrich Carsten, von Bueren André O, Kolevatova Larissa, Bernreuther Christian, Grob Tobias, Sepulveda-Falla Diego, van den Boom Leander, Westphal Manfred, Simon Ronald, Glatzel Markus

Abstract excerpt

PURPOSE: The aim of this study was to investigate the epidermal growth factor receptor (EGFR) status in ependymoma specimens, as there is a need for new prognostic and druggable targets in this disease. METHODS: Ependymomas (WHO grade II, n = 40; WHO grade III, n = 15) located spinal (n = 35), infratentorial (n = 14), and supratentorial (n = 6) of 53 patients with a median age of 40 (range, 2-79) years were...

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PMID: 26686534
DOI: 10.1007/s00381-015-2981-2

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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