Article
A novel interaction between the FLJ33534 locus and smoking in obesity: a genome-wide study of 14 131 Pakistani adults.
International journal of obesity (2005) - 1 Jan 2016
Ahmad S, Zhao W, Renström F, Rasheed A, Zaidi M, Samuel M, Shah N, Mallick N H, Shungin D, Zaman K S, Ishaq M, Rasheed S Z, Memon F-Ur-R, Hanif B, Lakhani M S, Ahmed F, Kazmi S U, Deloukas P, Frossard P, Franks P W, Saleheen D
Abstract excerpt
BACKGROUND: Obesity is a complex disease caused by the interplay of genetic and lifestyle factors, but identification of gene-lifestyle interactions in obesity has remained challenging. Few large-scale studies have reported use of genome-wide approaches to investigate gene-lifestyle interactions in obesity. METHODS: In the Pakistan Risk of Myocardial Infraction Study, a cross-sectional study based in Pakistan, we...
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