Association of a let-7 KRAS rs712 polymorphism with the risk of breast cancer.

doi:10.4238/2015.December.14.19

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Article

Association of a let-7 KRAS rs712 polymorphism with the risk of breast cancer.

Genetics and molecular research : GMR - 14 Dec 2015

Huang X, Yang Y, Guo Y, Cao Z L, Cui Z W, Hu T C, Gao L B

Abstract excerpt

Breast cancer (BC) is a common malignancy affecting women, with increasing incidences of this disease in China every year. Recent studies have extensively investigated a single nucleotide polymorphism in the let-7 miRNA binding site of the 3'-untranslated region of KRAS mRNA. The aim of this study was to determine the genotype frequency of the KRAS rs712 polymorphism, and evaluate its effect on BC risk. This...

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PMID: 26681038
DOI: 10.4238/2015.December.14.19

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KRAS

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