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Article

A let-7 KRAS rs712 polymorphism increases colorectal cancer risk.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014

Pan Xin-Min, Sun Rui-Fen, Li Zhao-Hui, Guo Xiao-Min, Zhang Zhen, Qin Hao-Jie, Xu Guo-Hui, Gao Lin-Bo

Abstract excerpt

Growing evidence has indicated that polymorphism present in the miRNA binding site of target gene can alter the ability of miRNAs to bind its target gene and modulate the development and progression of cancer. We aimed to investigate the association between let-7 KRAS rs712 polymorphism and the risk of colorectal cancer (CRC). The let-7 KRAS rs712 was analyzed in a case-control study, including 339 CRC patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23975373
DOI: 10.1007/s13277-013-1114-3

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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A let-7 KRAS rs712 polymorphism increases colorectal cancer risk.PMID 23975373Read ↗

A let-7 binding site polymorphism rs712 in the KRAS 3' UTR is associated with an increased risk of gastric cancer.Semantic proximity Read ↗

Significant association between Let-7-KRAS rs712 G > T polymorphism and cancer risk in the Chinese population: a meta-analysis.Semantic proximity Read ↗

Association of a let-7 KRAS rs712 polymorphism with the risk of breast cancer.Semantic proximity Read ↗

An let-7 KRAS rs712 polymorphism increases hepatocellular carcinoma risk.Semantic proximity Read ↗

Association of rs712 polymorphism in Kras gene 3'-luntranslated region and cancer risk: a meta-analysis.Semantic proximity Read ↗

Association between a functional polymorphism rs712 within let-7-binding site and risk of papillary thyroid cancer.Semantic proximity Read ↗

Association of Rs61764370 polymorphism within let-7 microRNA-binding site with lung cancer in Iranian population.Semantic proximity Read ↗

Protective effect of rs712 polymorphism in a let-7 microRNA-binding of KRAS gene in breast cancer of a Mexican population.Semantic proximity Read ↗

Role of KRAS let-7 LCS6 SNP in metastatic colorectal cancer patientsSemantic proximity Read ↗

Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).Semantic proximity Read ↗

KRAS SNPs are related to colorectal cancer susceptibility and survival in Chinese people.Semantic proximity Read ↗

Lack of association between let-7 binding site polymorphism rs712 and risk of nasopharyngeal carcinoma.Semantic proximity Read ↗

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