Article
Impact of KRAS variant rs61764370 on breast cancer morbidity.
Experimental oncology - 1 Dec 2015
Ustinova M, Daneberga Z, Bērziņa D, Nakazawa-Miklaševiča M, Maksimenko J, Gardovskis J, Miklaševičs E
Abstract excerpt
UNLABELLED: Low-penetrance gene variants and their combinations are topical study objects in breast cancer pathogenesis. Single nucleotide polymorphism rs61764370, localized in 3՛ UTR of KRAS gene, plays an important role in the development and progression of several cancers. The aim of our study was to determine the KRAS variant impact on breast cancer morbidity. PATIENTS AND METHODS: 2214 patients diagnosed...
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