Article
Association between KRAS gene polymorphisms and genetic susceptibility to breast cancer in a Chinese population.
Journal of clinical laboratory analysis - 1 Jan 2023
Jin Min, Lu Fengke, Li Xi, Zhou Wei, Li Sihui, Jiang Yanting, Wu Huiling, Wang Jian
Abstract excerpt
OBJECTIVE: The KRAS gene has a pathophysiological role in the development of many cancers. This study aims to investigate the relationship between KRAS polymorphisms and genetic susceptibility to breast cancer. METHOD: The rs712, rs12587 and rs9266 gene loci in the KRAS gene of 421 subjects (141 breast cancer patients, 141 benign breast tumours and 139 healthy controls) were analysed by the polymerase chain...
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