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Article

Prevalence of CYP2B6 polymorphisms in Argentinians: the role of genetic testing.

Genetics and molecular research : GMR - 11 Dec 2015

Scibona P, Vazquez C, Cajal A R, Argibay P F, Belloso W H

Abstract excerpt

CYP2B6 is a highly polymorphic isoenzyme involved in the metabolism of many drugs including cyclophosphamide, bupropion, and efavirenz. A single nucleotide polymorphism (SNP) in CYP2B6 (516G>T) resulted in decreased expression and function associated with the CYP2B6*6 haplotype. Among the clinical implications of this phenotype, decreased activation of cyclophosphamide and increased plasma levels of efavirenz...

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PMID: 26681005
DOI: 10.4238/2015.December.11.6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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