Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic granulomatous disease: Clinical, molecular, and therapeutic aspects.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 May 2016

Chiriaco Maria, Salfa Irene, Di Matteo Gigliola, Rossi Paolo, Finocchi Andrea

Abstract excerpt

Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by defects in the genes encoding any of the NADPH oxidase components responsible for the respiratory burst of phagocytic leukocytes. CGD is a genetically heterogeneous disease with an X-linked recessive (XR-CGD) form caused by mutations in the CYBB gene encoding the gp91(phox) protein, and an autosomal recessive (AR-CGD) form caused by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Infective Agents
Share to CYBA gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CYBB gene

Share to Genetic Therapy

Share to Granulomatous Disease, Chronic

Share to Hematopoietic Stem Cell Transplantation

Share to Mutation

Share to NADPH Oxidases

Source

Identifiers

PMID: 26680691
DOI: 10.1111/pai.12527

Genes

CYBA
CYBB
NCF1
NCF2
NCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic granulomatous disease: Clinical, molecular, and therapeutic aspects.PMID 26680691Read ↗

Genetic and biochemical background of chronic granulomatous disease.Semantic proximity Read ↗

[Chronic-granulomatous disease].Semantic proximity Read ↗

Chronic granulomatous disease: the solving of a clinical riddle at the molecular level.Semantic proximity Read ↗

Clinical and Immunological Characteristics of 63 Patients with Chronic Granulomatous Disease: Hacettepe Experience.Semantic proximity Read ↗

Genetic, biochemical, and clinical features of chronic granulomatous disease.Semantic proximity Read ↗

Chronic granulomatous disease.Semantic proximity Read ↗

Chronic granulomatous disease in Israel: clinical, functional and molecular studies of 38 patients.Semantic proximity Read ↗

Hematologically important mutations: X-linked chronic granulomatous disease (fourth update).Semantic proximity Read ↗

Hematologically important mutations: X-linked chronic granulomatous disease (third update).Semantic proximity Read ↗

Chronic granulomatous disease.Semantic proximity Read ↗

Chronic granulomatous disease: a 25-year patient registry based on a multistep diagnostic procedure, from the referral center for primary immunodeficiencies in Greece.Semantic proximity Read ↗

Hematologically important mutations: The autosomal forms of chronic granulomatous disease (third update).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.