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Article

Clinical and Immunological Characteristics of 63 Patients with Chronic Granulomatous Disease: Hacettepe Experience.

Journal of clinical immunology - 1 Jul 2021

Akar Halil Tuna, Esenboga Saliha, Cagdas Deniz, Halacli Sevil Oskay, Ozbek Begum, van Leeuwen Karin, de Boer Martin, Tan Cagman Sun, Köker Yavuz, Roos Dirk, Tezcan Ilhan

Abstract excerpt

BACKGROUND: Chronic granulomatous disease (CGD), one of the phagocytic system defects, is the primary immunodeficiency caused by dysfunction of the NADPH oxidase complex which generates reactive oxygen species (ROS), which are essential for killing pathogenic microorganisms, especially catalase-positive bacteria and fungi. OBJECTIVE: The objective of our study was to assess the clinical and laboratory...

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PMID: 33629196
DOI: 10.1007/s10875-021-01002-w

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