Article
The rs3024839 and rs2227483 polymorphisms with immune pathomechanism offers a starting point for diagnosis and susceptibility testing of myocardial infarction.
Scientific reports - 21 Feb 2026
Khosravi Nezhad Zahra, Dehghani Fateme, Molavizade Sina, Khanifar Hadi, Ashrafi Mehri, Azhdari Maryam, Faghih Abbasi Maryam, Baratvand Golshan, Naeimi Sirous, Khashei Varnamkhasti Khalil, Naeimi Raziyeh, Khashei Varnamkhasti Samire, Hemati Elham
Abstract excerpt
Long-term primary prevention of myocardial infarction faces challenges, but genetic risk assessment may change this dynamic. We sought for genetic risk loci influencing myocardial infarction and underlying pathomechanisms. AS-PCR used for mutation detection (STAT4_ rs3024839 and IL22_ rs2227483) and confirmed positives by sequencing and Digital PCR. STAT4 and IL22 mRNA levels and chromatin accessibility at SNP...
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