Article
Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms.
Epigenomics - 1 Jan 2016
Wong Doo Nicole, Makalic Enes, Joo JiHoon E, Vajdic Claire M, Schmidt Daniel F, Wong Ee Ming, Jung Chol-Hee, Severi Gianluca, Park Daniel J, Chung Jessica, Baglietto Laura, Prince Henry Miles, Seymour John F, Tam Constantine, Hopper John L, English Dallas R, Milne Roger L, Harrison Simon J, Southey Melissa C, Giles Graham G
Abstract excerpt
AIM: To examine whether peripheral blood methylation is associated with risk of developing mature B-cell neoplasms (MBCNs). MATERIALS & METHODS: We conducted a case-control study nested within a large prospective cohort. Peripheral blood was collected from healthy participants. Cases of MBCN were identified by linkage to cancer registries. Methylation was measured using the Infinium(®) HumanMethylation450....
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