Article
Molecular genetic and cytogenetic analysis of a primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma.
International journal of hematology - 1 Feb 2016
Kato Keisuke, Oh Yukiko, Takita Junko, Gunji Yuji, Kobayashi Chie, Yoshimi Ai, Nakao Tomohei, Noma Mio, Koike Kazutoshi, Morimoto Akira, Iijima Shigeko, Hojo Hiroshi, Tsuchida Masahiro
Abstract excerpt
We performed cytogenetic and molecular cytogenetic analyses of a primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma, a rare type of primary cutaneous T-cell lymphoma. G-banded analysis at initial diagnosis and recurrence revealed complex karyotype and clonal evolution reflecting genomic instability that parallels the aggressive clinical course observed. Spectral karyotyping...
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