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[Noninvasive prenatal screen of trisomy-21 using maternal plasma fetal free RNA allelic ratio].

Zhonghua fu chan ke za zhi - 1 Aug 2015

Xu Yajuan, Zhai Shanshan, Luo Xiaohua, Zhang Yingying, Ran Limin, Ren Lidan

Abstract excerpt

OBJECTIVE: Through the detections of the heterozygote frequencies tests of fetal specific genes PLAC4 and COL6A2 mRNA alleles in plasma of pregnant women, to explore its possibility of application in the noninvasive prenatal screenings of trisomy-21. METHODS: A toltal of 500 cases (males and females 250 cases respectively)of Han ethnic groups with Henan Provice of China who were subject to the physical checkup...

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PMID: 26675178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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