Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Improvement of detection of paternally inherited fetal mutant genes for β-globin in maternal plasma by PNA clamp].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2013

Huang Ken, Pan Hong-fei

Abstract excerpt

OBJECTIVE: To study improvement of detection of paternally herited fetal mutant genes for β-globin in maternal plasma by PNA clamp to seek a noninvasive prenatal diagnostic method for β-thalassemia. METHODS: A total of 38 maternal blood samples were collected at 7 to 20 weeks of gestation, samples in which the father carried CD41-42 mutation and mother carried normal gene or the other point mutation for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Globins
Share to beta-Thalassemia
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inheritance Patterns

Share to Mutant Proteins

Share to Peptide Nucleic Acids

Share to Pregnancy

Share to Prenatal Diagnosis

Source

Identifiers

PMID: 23683423
DOI: 10.3760/cma.j.issn.0253-2727.2013.03.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Improvement of detection of paternally inherited fetal mutant genes for β-globin in maternal plasma by PNA clamp].PMID 23683423Read ↗

[Genetic diagnosis of thalassemia mutations with free fetal DNA in pregnant plasma].Semantic proximity Read ↗

Detection of paternally inherited fetal point mutations for β-thalassemia in maternal plasma using simple fetal DNA enrichment protocol with or without whole genome amplification: an accuracy assessment.Semantic proximity Read ↗

Reliable detection of paternal SNPs within deletion breakpoints for non-invasive prenatal exclusion of homozygous α-thalassemia in maternal plasma.Semantic proximity Read ↗

Detection of paternal alleles in maternal plasma for non-invasive prenatal diagnosis of beta-thalassemia: a feasibility study in southern Chinese.Semantic proximity Read ↗

Noninvasive Prenatal Diagnosis of Beta-Thalassemia Disease by Using Digital PCR Analysis of Cell-Free Fetal DNA in Maternal PlasmaSemantic proximity Read ↗

The use of cell-free fetal DNA in maternal plasma for noninvasive prenatal linkage analysis in beta globin gene cluster.Semantic proximity Read ↗

[Diagnosis of several common alpha-thalassemia genotypes by multiplex fluorescence polymerase chain reaction].Semantic proximity Read ↗

[Noninvasive prenatal screen of trisomy-21 using maternal plasma fetal free RNA allelic ratio].Semantic proximity Read ↗

[Separation and enrichment of fetal nucleated red blood cells from maternal blood for non-invasive prenatal gene diagnosis].Semantic proximity Read ↗

[Gene Diagnosis and Phenotypic Analysis of β-Thalassemia Caused from a Rare Synonymous Mutation CD29 (C>T)].Semantic proximity Read ↗

[Accurate and rapid prenatal diagnosis of beta-thalassemia by a multiplex primer extension and denaturing high-performance liquid chromatography technique].Semantic proximity Read ↗

[Preimplantation genetic diagnosis for beta-thalassemia using whole genome amplification].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.