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Article

A non-invasive test for prenatal diagnosis based on fetal DNA present in maternal blood: a preliminary study.

Lancet (London, England) - 10 Feb 2007

Dhallan Ravinder, Guo Xin, Emche Sarah, Damewood Marian, Bayliss Philip, Cronin Michael, Barry Julie, Betz Jordan, Franz Kara, Gold Katie, Vallecillo Brett, Varney John

Abstract excerpt

BACKGROUND: Use of free fetal DNA to diagnose fetal chromosomal abnormalities has been hindered by the inability to distinguish fetal DNA from maternal DNA. Our aim was to establish whether single nucleotide polymorphisms (SNPs) can be used to distinguish fetal DNA from maternal DNA-and to determine the number of fetal chromosomes-in maternal blood samples. METHODS: Formaldehyde-treated blood samples from 60...

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Identifiers

PMID: 17292767
DOI: 10.1016/S0140-6736(07)60115-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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