Article
Noninvasive prenatal diagnosis of Down syndrome in samples from Southwest Chinese gravidas using pregnant plasma placental RNA allelic ratio.
Genetic testing and molecular biomarkers - 1 Sept 2012
Zhang Youcheng, Liu Hongqian, Chen Xinlian, Xie Xiaoyan, Liu Shanling, Wang He
Abstract excerpt
OBJECTIVE: The purpose of this research was to attempt a preliminary study of noninvasive prenatal diagnosis of Down syndrome in Southwest Chinese gravidas by using the plasma placental RNA allelic ratio. METHODS: The genotypes of the single-nucleotide polymorphisms (SNPs) located in the transcribed regions of the gene PLAC4 were detected in population samples collected in Southwest China by using polymerase...
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