Article
Sex determination using free fetal DNA at early gestational ages: a comparison between a modified mini-STR genotyping method and real-time PCR.
American journal of obstetrics and gynecology - 1 Sept 2012
Aghanoori Mohamad Reza, Vafaei Homeira, Kavoshi Hajar, Mohamadi Sanaz, Goodarzi Hamed R
Abstract excerpt
OBJECTIVE: Recently the use of free fetal deoxyribonucleic acid (DNA) in maternal plasma and serum has been applicable for noninvasive prenatal genetic diagnosis. In this study, we applied a new algorithmic base conventional polymerase chain reaction (PCR) genotyping method and also real-time PCR for detecting fetal X and Y-chromosome sequences in maternal plasma to determine fetal sex in pregnant women in their...
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