Article
The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices.
Biomaterials - 1 Oct 2012
Choi Yu Suk, Vincent Ludovic G, Lee Andrew R, Kretchmer Kyle C, Chirasatitsin Somyot, Dobke Marek K, Engler Adam J
Abstract excerpt
Cell patterning is typically accomplished by selectively depositing proteins for cell adhesion only on patterned regions; however in tissues, cells are also influenced by mechanical stimuli, which can also result in patterned arrangements of cells. We developed a mechanically-patterned hydrogel to observe and compare it to extracellular matrix (ECM) ligand patterns to determine how to best regulate and improve...
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