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Article

AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1

16 Dec 2015

Abstract excerpt

The aim of this study was to further our understanding of the transformation process by identifying differentially expressed proteins in melanocytes compared with melanoma cell lines. Tandem mass spectrometry incorporating iTRAQ reagents was used as a screen to identify and comparatively quantify the expression of proteins in membrane-enriched samples isolated from primary human melanocytes or three melanoma...

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PMID: 26672724
DOI: 10.1097/cmr.0000000000000228

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