Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Revisiting the Role of CD63 as Pro‐Tumorigenic or Anti‐Tumorigenic Tetraspanin in Cancers and its Theragnostic Implications

4 May 2023

Abstract excerpt

Cluster of differentiation antigen 63 (CD63) belongs to a superfamily of proteins, usually defined as tetraspanins which are known to transverse the bilayer membranes four times. The expression of CD63 has been shown to get altered in several cancers, where it has been demonstrated to act as both a tumor promoter and tumor suppressor. The present review describes the mechanism of how CD63 promotes tumor formation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Extracellular vesicles in disease
Share to Glycosylation and Glycoproteins Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37142558
DOI: 10.1002/adbi.202300078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Revisiting the Role of CD63 as Pro‐Tumorigenic or Anti‐Tumorigenic Tetraspanin in Cancers and its Theragnostic ImplicationsPMID 37142558Read ↗

Tetraspanin CD63 reduces the progression and metastasis of head and neck squamous cell carcinoma via KRT1-mediated cell cycle arrestSemantic proximity Read ↗

Tetraspanin CD9: A friend or foe of head and neck cancer (Review)Semantic proximity Read ↗

CD9, a tetraspanin target for cancer therapy?Semantic proximity Read ↗

ΔNp63α in cancer: importance and therapeutic opportunitiesSemantic proximity Read ↗

Tetraspanins in human epithelial malignanciesSemantic proximity Read ↗

p63-related signaling at a glanceSemantic proximity Read ↗

CD63 as a potential biomarker for patients with ovarian cancerSemantic proximity Read ↗

Taking Advantage of Basic Research: p63 Is a Reliable Myoepithelial and Stem Cell MarkerSemantic proximity Read ↗

Tetraspanins: Spanning from solid tumors to hematologic malignanciesSemantic proximity Read ↗

Sequential deletion of CD63 identifies topologically distinct scaffolds for surface engineering of exosomes in living human cellsSemantic proximity Read ↗

Tetraspanins as therapeutic targets in hematological malignancy: a concise reviewSemantic proximity Read ↗

Possible regulation of the immune modulator tetraspanin CD81 by alpha-synuclein in melanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.