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Article

AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma

1 Apr 2011

Abstract excerpt

The identification of genes that participate in melanomagenesis should suggest strategies for developing therapeutic modalities. We used a public array comparative genomic hybridization (CGH) database and real-time quantitative PCR (qPCR) analyses to identify the AMP kinase (AMPK)-related kinase NUAK2 as a candidate gene for melanomagenesis, and we analyzed its functions in melanoma cells. Our analyses had...

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PMID: 21460252
DOI: 10.1073/pnas.1007694108

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