Article
The genetics and pathogenesis of thoracic aortic aneurysm disorder and dissections.
Clinical genetics - 1 Jun 2016
Zhang L, Wang H-H
Abstract excerpt
Major advances have been made over the last 20 years to better elucidate the molecular basis of aortic aneurysmal diseases. Thoracic aortic aneurysm disorder and dissections (TAADs) have a high mortality rate, and one-fifth of TAADs patients have a high familial prevalence of the disease. Clinical presentations of TAADs are different, from no symptom to aortic insufficiency that may result in sudden death. The...
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