Article
Identification of a suppressor of retinal degeneration in Drosophila photoreceptors.
Journal of neurogenetics - 1 Sept 2012
Georgiev Plamen, Toscano Sarah, Nair Amit, Hardie Roger, Raghu Padinjat
Abstract excerpt
During sensory transduction, Drosophila photoreceptors experience substantial increases in intracellular Ca(2+) levels ([Ca(2+)](i)). Nevertheless in a number of mutants associated with excessive Ca(2+) influx through transient receptor potential (TRP) channels, Drosophila photoreceptors undergo loss of normal cellular structure manifest as a retinal degeneration. However, the molecular mechanisms that underpin...
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