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Article

Serum Amyloid A Facilitates Early Lesion Development in Ldlr-/- Mice.

Journal of the American Heart Association - 17 Jul 2015

Krishack Paulette A, Bhanvadia Clarissa V, Lukens John, Sontag Timothy J, De Beer Maria C, Getz Godfrey S, Reardon Catherine A

Abstract excerpt

BACKGROUND: Atherosclerosis is a chronic inflammatory disorder, and several studies have demonstrated a positive association between plasma serum amyloid A (SAA) levels and cardiovascular disease risk. The aim of the study was to examine whether SAA has a role in atherogenesis, the underlying basis of most cardiovascular disease. METHODS AND RESULTS: Mice globally deficient in acute-phase isoforms Saa1 and Saa2...

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Source

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Identifiers

PMID: 26187995
DOI: 10.1161/JAHA.115.001858
PMCID: PMC4608070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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