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Extramedullary hematopoiesis: Elucidating the function of the hematopoietic stem cell niche (Review)

27 Nov 2015

Abstract excerpt

Extramedullary hematopoiesis (EMH) occurs under various circumstances, including during embryonic/developmental periods, pathological status secondary to insufficient bone marrow function or ineffective hematopoiesis, in hematological disorders, for example malignancies, as well as stromal disorders of the bone. EMH is characterized by hematopoietic cell accumulations in multiple body locations. Common EMH...

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PMID: 26648325
DOI: 10.3892/mmr.2015.4621

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