Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VNTR polymorphisms of the IL-4 and IL-1RN genes and their relationship with frailty syndrome in Mexican community-dwelling elderly.

Aging clinical and experimental research - 1 Oct 2016

Pérez-Suárez Thalía Gabriela, Gutiérrez-Robledo Luis Miguel, Ávila-Funes José Alberto, Acosta José Luis, Escamilla-Tilch Mónica, Padilla-Gutiérrez Jorge Ramón, Torres-Carrillo Norma, Torres-Castro Sara, López-Ortega Mariana, Muñoz-Valle José Francisco, Torres-Carrillo Nora Magdalena

Abstract excerpt

Inflammation is a key event that is closely associated with the pathophysiology of frailty. The relationship of genetic polymorphisms into inflammatory cytokines with frailty remains poorly understood. The aim of this study was to investigate the association between VNTR polymorphisms of the IL-4 and IL-1RN genes with the risk of frailty. We included a sample of 630 community-dwelling elderly aged 70 and older....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disability Evaluation
Share to Frail Elderly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Geriatric Assessment

Share to Independent Living

Share to Interleukin 1 Receptor Antagonist Protein

Share to Interleukin-4

Share to Mexico

Share to Minisatellite Repeats

Source

Identifiers

PMID: 26646252
DOI: 10.1007/s40520-015-0503-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VNTR polymorphisms of the IL-4 and IL-1RN genes and their relationship with frailty syndrome in Mexican community-dwelling elderly.PMID 26646252Read ↗

Association of single nucleotide polymorphisms of IL-6 gene with frailty in the Chinese Bai nationality.Semantic proximity Read ↗

Altered immune system in frailty: Genetics and diet may influence inflammationSemantic proximity Read ↗

Genetically downregulated Interleukin-6 signalling is associated with a lower risk of frailtySemantic proximity Read ↗

DNA polymorphisms in inflammatory and endocrine signals linked to frailty are also associated with obesity: data from the FRASNET cohort.Semantic proximity Read ↗

PTPN22 gene functional polymorphism (rs2476601) in older adults with frailty syndrome.Semantic proximity Read ↗

Association between frailty phenotype, quantification of plasma HIV-1 RNA, CD4 cell count and HAART in HIV-positive subjects: a systematic review and meta-analysis of observational studies.Semantic proximity Read ↗

IL-10 and IL-1β Serum Levels, Genetic Variants, and Metabolic Syndrome: Insights into Older Adults' Clinical Characteristics.Semantic proximity Read ↗

IL-10 and IL-1β Serum Levels, Genetic Variants, and Metabolic Syndrome: Insights into Older Adults' Clinical CharacteristicsSemantic proximity Read ↗

Association of CRP gene polymorphisms with CRP levels, frailty and co-morbidity in an elderly Chinese population: results from RuLAS.Semantic proximity Read ↗

Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study.Semantic proximity Read ↗

Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing.Semantic proximity Read ↗

CRP 1846G>A polymorphism increases risk of frailty.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.