Article
Association between frailty phenotype, quantification of plasma HIV-1 RNA, CD4 cell count and HAART in HIV-positive subjects: a systematic review and meta-analysis of observational studies.
AIDS care - 1 Sept 2022
Melo Géssyca Cavalcante, Carvalho Aline Carla Araújo, Mendes Mário Luis Tavares, do Nascimento Renee Oliveira, de Araújo Karina Conceição Gomes Machado, Tanajura Diego Moura, Santos Victor Santana, Martins-Filho Paulo Ricardo
Abstract excerpt
HIV infection causes a constant activation of the immune system and contributes to an enhanced systemic pro-inflammatory cytokine milieu, which has been associated with premature aging and frailty. We performed a systematic review and meta-analysis to analyze whether the HIV-1 RNA load, CD4+ T-lymphocyte counts and exposure to HAART in HIV-positive subjects are associated with frailty phenotype. Searches were...
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