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Article

Ikaros, Helios, and Aiolos protein levels increase in human thymocytes after β selection.

Immunologic research - 1 Apr 2016

Mitchell Julie L, Seng Amara, Yankee Thomas M

Abstract excerpt

In human T cell development, the mechanisms that regulate cell fate decisions after TCRβ expression remain unclear. We defined the stages of T cell development that flank TCRβ expression and found distinct patterns of human T cell development. In half the subjects, T cell development progressed from the CD4(-)CD8(-) double-negative stage to the CD4(+)CD8(+) double-positive (DP) stage through an immature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell, alpha-beta

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Source

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Identifiers

PMID: 26645971
DOI: 10.1007/s12026-015-8754-x
PMCID: PMC4814933

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Ikaros, Helios, and Aiolos protein levels increase in human thymocytes after β selection.PMID 26645971Read ↗

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Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignanciesSemantic proximity Read ↗

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