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Article

Searching for the Optimal Predictor of Ciprofloxacin Resistance in Klebsiella pneumoniae by Using In Vitro Dynamic Models.

Antimicrobial agents and chemotherapy - 7 Dec 2015

Strukova Elena N, Portnoy Yury A, Romanov Andrey V, Edelstein Mikhail V, Zinner Stephen H, Firsov Alexander A

Abstract excerpt

There is growing evidence of applicability of the hypothesis of the mutant selection window (MSW), i.e., the range between the MIC and the mutant prevention concentration (MPC), within which the enrichment of resistant mutants is most probable. However, it is not clear if MPC-based pharmacokinetic variables are preferable to the respective MIC-based variables as interstrain predictors of resistance. To examine...

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Identifiers

PMID: 26643328
DOI: 10.1128/AAC.02334-15
PMCID: PMC4775939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Searching for the Optimal Predictor of Ciprofloxacin Resistance in Klebsiella pneumoniae by Using In Vitro Dynamic Models.PMID 26643328Read ↗

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