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Article

Metastatic phenotype in CWR22 prostate cancer xenograft following castration.

The Prostate - 1 Mar 2016

Seedhouse Steven J, Affronti Hayley C, Karasik Ellen, Gillard Bryan M, Azabdaftari Gissou, Smiraglia Dominic J, Foster Barbara A

Abstract excerpt

BACKGROUND: CWR22 is a human xenograft model of primary prostate cancer (PCa) that is often utilized to study castration recurrent (CR) PCa. CWR22 recapitulates clinical response to androgen deprivation therapy (ADT), in that tumors regress in response to castration, but can recur after a period of time. METHODS: Two cohorts of mice, totaling 117 mice were implanted with CWR22, allowed to develop tumors,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26642837
DOI: 10.1002/pros.23127
PMCID: PMC4745026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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