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Identification of differentially expressed genes associated with androgen‐independent growth of prostate cancer

23 May 2002

Abstract excerpt

BACKGROUND: The human prostate cancer xenograft, CWR22, similar to most human prostate cancers, regresses after castration and recurs several months after the removal of androgen. Genes uniquely associated with proliferation were identified by comparison of tumors that exist in androgen absence but differ in proliferative capacity. METHODS: cDNA libraries from CWR22 tumors from 20-day castrate mice (proliferation...

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PMID: 11987153
DOI: 10.1002/pros.10086

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