Article
Adenovirus-specific T-cell Subsets in Human Peripheral Blood and After IFN-γ Immunomagnetic Selection.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2016
Qian Chongsheng, Wang Yingying, Cai Huili, Laroye Caroline, De Carvalho Bittencourt Marcelo, Clement Laurence, Stoltz Jean-François, Decot Véronique, Reppel Loïc, Bensoussan Danièle
Abstract excerpt
Adoptive antiviral cellular immunotherapy by infusion of virus-specific T cells (VSTs) is becoming an alternative treatment for viral infection after hematopoietic stem cell transplantation. The T memory stem cell (TSCM) subset was recently described as exhibiting self-renewal and multipotency properties which are required for sustained efficacy in vivo. We wondered if such a crucial subset for immunotherapy was...
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