Article
Induction of Thelper1-driven antiviral T-cell lines for adoptive immunotherapy is determined by differential expression of IFN-γ and T-cell activation markers.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2000
Leibold Josef, Feucht Judith, Halder Ameli, Stevanovic Stefan, Kayser Simone, Handgretinger Rupert, Feuchtinger Tobias
Abstract excerpt
Viral infections with cytomegalovirus (CMV) or human adenovirus (HAdV) after stem cell transplantation are still associated with a high morbidity and mortality. Transfer of T-cell immunity from a healthy individual to a stem cell transplant recipient, known as adoptive T-cell transfer, has been shown to be effective to prevent viral complications. Treatment efficacy will depend on the availability of functional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
