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Genetic Insights into Interleukin-13 Polymorphisms in Colorectal Cancer Risk and Progression.

Cancer genomics & proteomics - 1 Jan 2026

Yueh Te-Cheng, Ke Tao-Wei, Wang Jiaqi, Deng Yang, Hung Yi-Chih, Huang Cheng-Wei, Chang Yu-Chen, Tsai Chia-Wen, Chang Wen-Shin, Gu Jian, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: Colorectal cancer (CRC) is a major global health burden with increasing incidence and significant mortality, particularly in advanced stages. Genetic susceptibility and inflammation-related pathways, including cytokine signaling, are increasingly recognized as key contributors to CRC pathogenesis. Interleukin-13 (IL-13) polymorphisms, particularly rs1800925 and rs20541, have been implicated in...

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PMID: 42373222
DOI: 10.21873/cgp.20597
PMCID: PMC13321704

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