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Article

Molecularly targeted therapies for acute myeloid leukemia.

Hematology. American Society of Hematology. Education Program - 1 Jan 2015

Stein Eytan M

Abstract excerpt

The past 15 years have seen major leaps in our understanding of the molecular genetic mutations that act as drivers of acute myeloid leukemia (AML). Clinical trials of agents against specific mutant proteins, such as FLT3-internal tandem duplications (ITDs) and isocitrate dehydrogenase mutations (IDHs) are ongoing. This review discusses agents in clinical trials that target specific gene mutations and/or...

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Source

Identifiers

PMID: 26637775
DOI: 10.1182/asheducation-2015.1.579

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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