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Freeze-thaw Caenorhabditis elegans freeze-thaw stress response is regulated by the insulin/IGF-1 receptor daf-2.

BMC genetics - 3 Dec 2015

Hu Jian-Ping, Xu Xiao-Ying, Huang Li-Ying, Wang Li-shun, Fang Ning-Yuan

Abstract excerpt

BACKGROUND: Adaption to cold temperatures, especially those below freezing, is essential for animal survival in cold environments. Freezing is also used for many medical, scientific, and industrial purposes. Natural freezing survival in animals has been extensively studied. However, the underlying mechanisms remain unclear. Previous studies demonstrated that animals survive in extremely cold weather by avoiding...

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PMID: 26635120
DOI: 10.1186/s12863-015-0298-5
PMCID: PMC4669615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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