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Article

Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.

Science (New York, N.Y.) - 28 Jun 2002

Scott Barbara A, Avidan Michael S, Crowder C Michael

Abstract excerpt

To identify genetic determinants of hypoxic cell death, we screened for hypoxia-resistant (Hyp) mutants in Caenorhabditis elegans and found that specific reduction-of-function (rf) mutants of daf-2, an insulin/insulinlike growth factor (IGF) receptor (INR) homolog gene, were profoundly Hyp. The h...

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PMID: 12065745
DOI: 10.1126/science.1072302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12065745-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.PMID 12065745Read ↗

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