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Article

Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes.

Methodist DeBakey cardiovascular journal - 1 Jan 2000

Connell Jennifer P, Kodali Santhisri, Cooke John P

Abstract excerpt

The technological development of induced pluripotent stem cells (iPSCs) has overcome many of the limitations of adult and embryonic stem cells. We have found that activation of innate immunity signaling is necessary for this process, as it facilitates epigenetic plasticity in cells by a process called transflammation. More recently, we have discovered that transflammation also facilitates the transdifferentiation...

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Identifiers

PMID: 26634026
DOI: 10.14797/mdcj-11-3-176
PMCID: PMC4666425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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