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Genetic modification and preconditioning strategies to enhance functionality of mesenchymal stromal cells: a clinical perspective

19 Apr 2023

Abstract excerpt

INTRODUCTION: Mesenchymal stromal cell (MSC)-based therapy has generated great hope for the treatment of various diseases such as myocardial infarction and stroke. Unfortunately, MSC-based therapy faces major hurdles in its translation to clinical practice. To address these issues, preconditioning and genetic modification strategies have been developed. Through preconditioning, MSCs are cultured under sub-lethal...

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PMID: 37073114
DOI: 10.1080/14712598.2023.2205017

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