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The APL1 immune factor is encoded by a single ancestral gene in most <i>Anopheles</i> species and expanded to three paralogs with distinct function in the <i>Anopheles gambiae</i> complex

2019-09-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The recent reference genome assembly and annotation of the Asian malaria vector Anopheles stephensi revealed only one gene encoding the leucine-rich repeat immune factor APL1, while in Anopheles gambiae and sibling Anopheles coluzzii , APL1 factors are encoded by a family of three paralogs. The phylogeny and biological function of the unique APL1 gene in A. stephensi hav...

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Literature Corpus work
9ae0c914-d963-5177-b105-f309579f50a8
DOI
10.1101/785089
Open publication

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The APL1 immune factor is encoded by a single ancestral gene in most <i>Anopheles</i> species and expanded to three paralogs with distinct function in the <i>Anopheles gambiae</i> complexDOI 10.1101/785089
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