A novel polymorphism near HLA class II region is associated with spontaneous clearance of HCV and response to interferon treatment in Chinese patients.

doi:10.1038/jhg.2015.145

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Article

A novel polymorphism near HLA class II region is associated with spontaneous clearance of HCV and response to interferon treatment in Chinese patients.

Journal of human genetics - 1 Apr 2016

Xu Yin, Huang Peng, Yue Ming, Su Jing, Chen Hongbo, Chen Mingzhu, Wang Jie, Li Jun, Peng Zhihang, Zhang Yun, Yu Rongbin

Abstract excerpt

A recent genome-wide association study (GWAS) has identified the single-nucleotide polymorphism (SNP) rs4273729 in a 100-kbp region comprising human leukocyte antigens (HLAs) class II genes as an important predictor of hepatitis C virus (HCV) clearance in European and African populations. This study was to determine whether this polymorphism is also associated with spontaneous HCV clearance as well as response to...

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PMID: 26632884
DOI: 10.1038/jhg.2015.145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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