Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The overshoot and phenotypic equilibrium in characterizing cancer dynamics of reversible phenotypic plasticity.

Journal of theoretical biology - 7 Feb 2016

Chen Xiufang, Wang Yue, Feng Tianquan, Yi Ming, Zhang Xingan, Zhou Da

Abstract excerpt

The paradigm of phenotypic plasticity indicates reversible relations of different cancer cell phenotypes, which extends the cellular hierarchy proposed by the classical cancer stem cell (CSC) theory. Since it is still questionable if the phenotypic plasticity is a crucial improvement to the hierarchical model or just a minor extension to it, it is worthwhile to explore the dynamic behavior characterizing the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Cell Dedifferentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Cell Proliferation

Share to Feedback, Physiological

Share to Models, Biological

Share to Neoplasms

Share to Neoplastic Stem Cells

Source

Identifiers

PMID: 26626088
DOI: 10.1016/j.jtbi.2015.11.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The overshoot and phenotypic equilibrium in characterizing cancer dynamics of reversible phenotypic plasticity.PMID 26626088Read ↗

The phenotypic equilibrium of cancer cells: From average-level stability to path-wise convergence.Semantic proximity Read ↗

Dynamics between Cancer Cell Subpopulations Reveals a Model Coordinating with Both Hierarchical and Stochastic ConceptsSemantic proximity Read ↗

Cancer Cell Plasticity: Rapid Reversal of Chemosensitivity and Expression of Stemness Markers in Lung and Breast Cancer Tumorspheres.Semantic proximity Read ↗

Nonequilibrium population dynamics of phenotype conversion of cancer cells.Semantic proximity Read ↗

Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation.Semantic proximity Read ↗

The phenotypic reversion of cancer: Experimental evidences on cancer reversibility through epigenetic mechanisms (Review).Semantic proximity Read ↗

A kinetic model of multiple phenotypic states for breast cancer cells.Semantic proximity Read ↗

Overshoot during phenotypic switching of cancer cell populations.Semantic proximity Read ↗

Mathematical modeling and quantitative analysis of phenotypic plasticity during tumor evolution based on single-cell data.Semantic proximity Read ↗

Do cancer cells undergo phenotypic switching? The case for imperfect cancer stem cell markers.Semantic proximity Read ↗

The invasion of de-differentiating cancer cells into hierarchical tissuesSemantic proximity Read ↗

A Bayesian statistical analysis of stochastic phenotypic plasticity model of cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.